Vitamin D and corona controversy until when?

Articles demonstrating the effectiveness of vitamin D on the novel coronavirus infection (Corona 19), as well as news about health professionals and politics who support it, are accumulating daily from around the world.

On February 23, the Irish Parliament held a public hearing with members of the Health Commission’s Senate and House of Representatives and medical professionals on vitamin D deficiency and COVID-19 symptoms. It was made at the request of the Covit-D Consortium, which demanded the establishment of a vitamin D policy for responding to COVID-19.

Glenn Grossman, the 6th Congressman in Wisconsin, USA, announced a resolution last week. This is a content that acknowledges the effectiveness of vitamin D in preventing respiratory diseases and corona 19 complications. Grossman asked the Centers for Disease Control and Prevention (CDC) and the Food and Drug Administration (FDA) to enact a law that publishes a guide to taking vitamin D for Corona 19.

In addition, three legislators from both sides of the Michigan state government, along with local health professionals, stressed the importance of vitamin D. It was said that an easy and inexpensive way to actively respond to corona infection is to consume enough vitamin D every day.

On the other hand, Hokuyama Hidehiro, Deputy Director of the Riken Institute of Japan, which boasts a history of 100 years, developed the’Adjuvant vaccine’ with vitamin D added to the Corona 19 vaccine to enhance immunity on February 22. Announced that they are doing.

Yet, to date, mainstream health professional groups and policy makers are still hesitant to speak of the lack of evidence for vitamin D. Recently, some medical scientists have published a paper that lacks evidence that vitamin D prevents the worsening of Corona 19.

In this situation, Professor Richard Camona of the Department of Public Health at the University of Arizona, who served as the 17th Surgeon General in the U.S., proposed the condition of Hill and appealed to policy authorities as soon as possible for the supply of vitamin D. Are in sync.

‘Hill’s Condition’ is a criterion suggested by Dr. Austin Bradford Hill of England, the head of medical statistics, and is used to establish a causal relationship when an experiment is impossible.

Dr. Hill is a scholar who laid the foundation for modern randomized controlled experiments by publishing the first randomized controlled experiment paper in the medical world to determine the effectiveness of threptomycin, a tuberculosis drug, in 1948. In 1962, the causal relationship between smoking and lung cancer, which was impossible for a randomized controlled experiment, was discovered through observational experiments, and after that, nine criteria for determining the causal relationship were established. Based on this criterion, epidemiologists can present the possibility of a causal relationship without rigorous experimentation.

① Strength of the association: What is the strength of the association between cause and effect?
② Consistency: Are similar results presented in other studies?
③ Specificity of relevance: Are the risk factors associated with one disease?
④ Temporality between factor exposure and disease occurrence: Does cause precede effect?
⑤ Biological degree (Biologic gradient or dose-response relationship): As exposure increases, does the result increase proportionally?
⑥ Biological plausibility: Is it possible to explain according to biological science principles?
⑦ Existing theory and coherence: Is it possible to explain harmoniously with existing knowledge and theory?
⑧Experiment: Does elimination of possible causes result in a reduction in disease risk?
⑨ Similarity to other existing causal relationships: Is it similar to an already revealed link?

Professor Kamona reviewed the experimental paper on the correlation between vitamin D and Corona 19 published so far, and proved that “vitamin D deficiency is the cause of increasing the risk factors of Corona 19” based on the above nine criteria.

So far, experiments in India, Singapore, the UK (Newcastle), Iran, Turkey, Mexico, France, and Russia (St. Petersburg) have shown that low vitamin D levels exacerbate the symptoms of COVID-19. In addition, experimental results in Italy (Bari), the United States (Chicago, Boston), Israel, Spain (Santander), Germany (Heidelberg), and Iran (Tehran) showed the predictability that low vitamin D levels increase COVID-19 infection. Experimental results in Singapore and Spain (Cordoba) have shown that vitamin D is effective in treating pneumonia in patients with COVID-19.

Many people have already died from Corona 19. In recent years, new strains of virus have emerged, and concerns are growing about how effective the current vaccine will be. Prof. Camona’s desperate cry, “Waiting for the perfect evidence to come out, we can’t make Corona 19 patients die from vitamin D deficiency anymore,” I hope that domestic medical and quarantine experts will also listen.

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