Viagra may be useful against Alzheimer’s disease

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U.S. brain researchers say anti-impotence Viagra tablets may be an effective treatment for people with Alzheimer’s disease.

According to a study described by the BBC news portal researchers in Cleveland studied the effects of Viagra in the brain. Testing of the cells has shown that the drug targets some proteins that contribute to the development of this form of dementia.

The researchers also analyzed a six-year database of about seven million patients and found that Men taking Viagra had a lower risk of developing Alzheimer’s disease.

Their study, published in a recent issue of the journal Nature Aging, indicated that further research is needed on this issue. Experts say such research is exciting because a different use of an existing drug can be a faster, simpler, and cheaper response to developing a brand new drug.

Viagra, which contains the active substance sildenafil, was originally designed to be used as a heart medicine because it improves blood flow by relaxing or dilating the blood vessels. It was later discovered that has a similar effect elsewhere in the body, including the penile arteries, and therefore successfully treats erectile dysfunction.

However, experts say there may be other uses. Sildenafil is already used in both men and women for pulmonary hypertension, ie for the treatment of impaired blood supply to the lungs.

It has also recently been studied whether the drug can help patients with vascular dementia, the second most common form of dementia. The results of the new study suggest that Alzheimer’s disease may be a successful treatment option. Bprice The exact cause of the disease is unknown, but it has already been discovered that abnormal protein deposits form in the brains of patients.

The Cleveland research team found that taking more than normal of the medicine has improved the growth of brain cells, and reduced the formation of protein deposits in laboratory experiments with human tissues.

Feixiong Cheng, the head of the research said that aftern found a link between the use of sildenafil and a reduction in the risk of Alzheimer’s diseaset, in the next phase, randomized clinical trials will be performed to demonstrate the theory and to confirm the clinical use of sildenafil against Alzheimer’s.

An expert in brain research, Tara Spires-Jones – who is doing research at the University of Edinburgh – also stressed the need for further studies to prove the drug’s effectiveness against Alzheimer’s. As you said: while the data from the study are scientifically promising, it would not start taking sildenafil to prevent the disease.


Source: Patika Magazin Online by www.patikamagazin.hu.

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