Scientists have succeeded in rejuvenating skin cells by 30 years. There is hope for slowing down aging – Man – Science and technology

Researchers at Cambridge University have succeeded in rejuvenating the skin cells of a 53-year-old woman to the shape of a 23-year-old man. They hope that their knowledge will be used in the future to rejuvenate cells and other body organs.

The aim of the research is to develop the treatment of age-related diseases, such as diabetes, heart disease and neurological disorders. The head of the research, Professor Wolf Reik, said in an interview with the BBC news station that he hopes that one day it will be possible to keep the health of the elderly for longer. “It simply came to our notice then. “Many common problems become serious illnesses with age, and it’s amazing to figure out how to help people,” he said.

Procedures known from research that led to the birth of the cloned Dolly sheep were used to rejuvenate the skin. The result of the Cambridge team was published in the eLife magazine, and Reik pointed out that this was a research at a very early stage.

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Many problems need to be overcome before technology can be transferred from the laboratory to the clinic. However, the fact that it has been possible for the first time to show that skin rejuvenation is possible is an important step forward. The starting point of the research was findings from the Roslin Institute in Edinburgh, where a sheep was cloned from an adult’s skin cell in the 1990s. The original goal of the Roslin Institute team was not to create clones of animals or humans, but human embryonic stem cells that could grow in certain tissues such as muscles, cartilage or nerve cells to replace depleted organs.

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The technology was later simplified by Japanese scientist Shinja Yamanaka, a Nobel laureate in medicine and physiology. He was able to create an induced pluripotent stem cell, which is artificially prepared and can become any cell in the adult organism. Its method is called IPS.

In the case of both Dolly cloning and IPS, the stem cells must grow into the cells and tissues needed by the patient. It is a complex process and, despite many years of efforts, its usefulness in the treatment of diseases is very limited. Reikov’s team used the IPS technique on the skin cells of a 53-year-old woman, reducing the length of their stay in the chemical from 50 to 12 days.

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Team member Dilgeet Gill said he was stunned to find that the cells had not turned into embryonic stem cells, but were “rejuvenated” by looking and behaving as if they had been taken from a 23-year-old man. The process cannot be implemented quickly in clinics because the IPS method increases the risk of cancer. Reik said he believed that now that it was clear that cells could be rejuvenated, his group could come up with an alternative and safe technology. “The ultimate goal is to prolong people’s health, not their lives, so people can age healthier,” he said.


Source: Pravda – Veda a technika by vat.pravda.sk.

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