“Pigs could be breeding grounds for super bacteria” (Study)

Pigs can be a breeding ground for super bacteria, a study has found. [사진=게티이미지뱅크]
Overuse of antibiotics in pig farms can make pigs a breeding ground for super bacteria, a study has published. The British Guardian reported on the 24th based on the results of the Danish researchers presented at the ‘2022 European Society for Clinical Microbiology and Infectious Diseases (ECCMID)’ held in Lisbon, Portugal from the 23rd to the 26th (local time).

A research team consisting of Professor Dort Fries of the University of Copenhagen in Denmark, Dr. Semih Besauy, and Dr. Søren Persson of the National Serum Research Institute of Denmark, said, “Clostridioides difficile (C difficile) from farm pigs was found in the hospital. It was found that the genes of the hospitalized patients were consistent with the resistant bacteria.” “Our findings show that C difficile is a storehouse of antimicrobial resistance genes that can be exchanged between animals and humans,” said Dr. Bejaui. “It suggests that there is, and confirms the linkage of the resistance chain from animal farms to humans.”

All but three of the currently used antibiotics are resistant to C difficile, so it is classified as the most threatening super bacterium in developed countries. Infection with this bacterium can cause enteritis and fatal diarrhea in the elderly and hospitalized patients. In the United States, in 2017, 223,900 people were infected with C difficile, and 12,800 people died, and it is estimated that medical expenses of more than $1 billion were incurred.

The researchers collected 514 pig feces samples from 14 Danish farms and slaughterhouses between 2020 and 2021. C difficile was detected in 54 out of 514 pig samples. It was detected more in sows and piglets than in slaughtered pigs. The researchers interpreted that the composition of the gut microbiome of young pigs is because they are vulnerable to C difficile.

The researchers compared the pig samples with 934 samples collected from patients hospitalized for C difficile infection during the same period. As a result of the analysis, all 13 genotypes of C difficile found in pigs were also found in fecal samples from hospitalized patients. Among them, the ST11 type was the most common and similar. The ST11 type was found in 21 pig samples and 270 human samples. The researchers found that 16 of those cases had the same genotype of C difficile between humans and pigs.

“We found that the mutation isolated from pigs was genetically identical to the mutation found in humans over the same period of time,” said Dr. Bejaui. It shows that it will infect humans.” He pointed out, “What is particularly worrisome is that C difficile stores a large number of genes that transmit resistance to aminoglycoside, one of the antibiotics, so it can spread to other species.”

Scientists have warned that overuse of antibiotics, even for minor infections, can later lead to a flourishing of ineffective super bacteria. In particular, it was pointed out that the abuse of antibiotics to prevent diseases while densely raising livestock on farms is aggravating this problem. According to the International Cancer Control Coalition, 750,000 people worldwide die each year from infection with antibiotic-resistant superbacteria. estimated

The press release of the announcement can be found at the following link (https://www.eurekalert.org/news-releases/950551).

By Han Gun-pil, reporter [email protected]

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