Pig kidney function in human experiment Science


The pig kidney was transplanted into the human body for the first time in late September. The person who received the kidney was already brain dead at the time of the transplant.

However, the kidney worked. It also began to filter urine normally in a person whose vital functions were maintained by doctors.

The trial at a New York hospital lasted 54 hours, he says website Science Alert. There is no peer-reviewed study in the experiment yet.

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According to the transplant doctors, the experiment showed that pig organs can be transplanted into humans quite soon. It saves lives.

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The transfer was hampered by the fact that the single sugar produced by porcine cells is foreign to the human body and defense system. So the human body rejects it.

Therefore, the kidney used in the experiment was genetically engineered. Thus, the kidney was tested on a genetically modified animal.

The sugar that was rejected by the human body had been removed from the pig. Thus the defense of the human body did not rise against the foreign kidney, according to the news agency AFP.

In the experiment, surgeons secured the pig’s kidney into a dead woman’s blood vessels and bloodstream.

The veins had been surgically moved outside the dead body. This made it easier for surgeons to monitor the function of the graft.

Throughout the experiment, the graft did what it was supposed to do. It filtered the waste products from the human body and produced urine. It was not rejected by the human body.

“The kidney was working perfectly normally,” the surgeon said Robert Montgomery news agency for AFP. He led the experiment.

When the pig’s kidneys were tested, the researchers maintained the body’s vital signs during the experiment. Relatives agreed to the experiment.

While living, the woman wanted her organs to be donated for medical use. Organs would no longer be eligible for traditional transplants.

“This went better than we hoped,” Montgomery said of the experiment To USA Today.

Montgomery itself received an organ transplant three years ago, in another person’s heart.

“I was one of those who lay in the intensive care unit waiting and didn’t know if I would get a new body in time,” he said.

Several biotechnology companies have begun to develop suitable pig organs for transplantation. They would ease the organ shortage of patients.

In the United States, more than 90,000 people queue for a kidney. Every day, at least 12 of them die waiting for a transplant, says the website Science Alert.

The experiment on the pig kidney was a winning win To Revivicor. Revivicor raised one hundred pigs for the experiment. They lived under strict supervision on a farm in the state of Iowa.

Last December in the United States Food and Drug Administration FDA approved Revivicor genetically modified pigs for the experiment.

However, the FDA requires further investigation before a pig’s organ can be transplanted into living humans.

According to experts, the pig kidney would be given to people who have no other options. The first ones would get a kidney in maybe two years.


Source: Tiede by www.tiede.fi.

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