“Omicron contagious but with less serious effects”

«We still need a week to complete the analyzes and studies, but from the information we have today it seems more contagious but with a less important clinical case history. This means that the virus is adapting better to the host with fewer effects in terms of possible serious consequences and mortality ». This was stated by the virologist Fabrizio Pregliasco, member of the Cts of Lombardy and medical director of the Galeazzi hospital in Milan, to Affaritaliani.it.

“There is no confirmation that the Omicron variant avoids vaccines and with three doses the effectiveness should be guaranteed – he added -. So far, computer analyzes have been done with evaluations performed by comparing the sequences. It emerges that the Omicron variant only modifies the S1 of the spike (a sort of hook of the virus), therefore it changes the contagiousness capacity. But the S2, which concerns the pathogenicity and therefore the dangerousness, is not modified and this makes us think. In a still not validated study, researchers have shown insertions of rhinovirus pieces caused by a coinfection in a subject. These modifications inserted in the genome could lead to an improvement and a pathogenic reduction of the Covid virus “.

“Fourth dose to be evaluated”

As for the fourth dose of the vaccine “it should be evaluated in the near future, also and above all on the basis of the trend of the epidemic. The virus – says Pregliasco – moves with waves that follow one another like those of a stone in the pond, there are important waves and others that go to reduce. The original wave would be less important if there were variations. Having said this, it is possible that the possible fourth dose is no longer universal but targeted, like the anti-flu vaccination, for the most fragile, elderly and exposed people. It could be free only for the risk groups. As to the timing it is impossible to say today because we do not know the effect of the third dose, even if its effectiveness should guarantee long-term protection. The first two doses gave an imprinting, the third, which is called a booster, is used to strengthen protection over time “.

Source: by www.diariodelweb.it.

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