Muscle weakening is caused by this disease

The first symptom may be that it becomes more and more difficult to chew while eating because the masticatory muscles get tired and then regain strength after a little rest. About an autoimmune disease called myasthenia gravis, dr. János Kádár, immunologist and chief physician of the Immun Center, provides more information.

Closing eyelids, poor eyesight

Myasthenia gravis can be a sign if the muscles feel weak, they get tired even on a small load, and then this condition improves at rest. The symptoms are more intense or barely present, as the disease is characterized by an exacerbation of the symptoms after a temporary improvement. A characteristic symptom is a weakening of the muscles that move the eyes, the eyelids of the affected people close, they have difficulty keeping their eyes open, and blurred or double vision may occur.

Tired muscles

One does not even think that during the performance of our basic daily tasks, every movement requires the coordinated operation of several muscles. In addition to moving the eyelids, chewing, swallowing, smiling, climbing stairs, or a handshake is also serious muscle work when we need to perform it with weak and tiring muscles. Myasthenia gravis is the most serious, life-threatening complication if the disease also affects the muscles needed for breathing.

The organization destroys itself

As with autoimmune diseases in general, the causes of myasthenia gravis are unknown. It has been observed to be more common in women between the ages of 20 and 40 and in men between the ages of 50 and 70. The autoimmune The essence of these processes is that the patient’s immune system mistakenly launches an attack on his own body, in this case the substance used to transmit messages between nerves and muscles, acetylcholine. Stakeholders start producing antibodies against acetylcholine receptors, which is why muscle contraction does not work perfectly.

A possible trigger?

Thyroid cancer occurs in 15% of patients. In most cases, the lesion is benign, and surgical removal of the thymus gland also improves the symptoms of myasthenia gravis in some patients. Although the disease is incurable, so-called combined immunomodulatory therapy can significantly reduce symptoms and maintain a good quality of life for patients. The therapy is personalized and takes longer to set up.

Source: Immune center

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