Research by Professor Jong-Hoon Ryu’s team,’The effect of improving menopausal syndrome of Kyungok High School’
|[서울=뉴시스] Professor Jong-Hoon Ryu, Department of Oriental Pharmacy, Kyunghee University (Photo Credit=Kwangdong Pharmaceutical)|
[서울=뉴시스] Reporter Song Yeon-joo = Professor Ryu Jong-hoon of the College of Pharmacy at Kyung Hee University announced on the 13th that the research team has announced an animal experiment related to the efficacy of the oriental medicine’Kyungokgo’ in improving menopausal symptoms.
Prof. Ryu’s team confirmed that Gyeongok High can have an improvement effect on depression and cognitive decline in an animal experimental study entitled’The Effect of Improving Menopausal Syndrome of Gyeongok High School Using an Ovariectomy Animal Model’.
Menopause is a time when the ovaries gradually lose their function. It means 3-4 years before and after menopause. As the secretion of the female hormone estrogen decreases below the required level, facial flushing, genital atrophy, dysuria, osteoporosis, abnormal lipid metabolism, depression, memory loss, insomnia, and skin aging appear.
Among various symptoms, the research team tested the improvement effect of Gyeongokgo on’depression’ and’reduction of cognitive function’. As a result of a forced swimming experiment in rats for which menopausal symptoms were artificially induced by oophorectomy, the effect of improving depression was confirmed when Gyeongokgo 600 mg/kg and 1800 mg/kg were administered for 8 weeks. In the’evaluation of a new object recognition experiment’, he explained that the cognitive function, which was reduced by menopause, was significantly increased in all doses of Kyungok High. In particular, Gyeongokgo 600mg/kg had a significant effect when compared with the group administered with estradiol, a female hormone that improves menopausal symptoms.
In the’Y-shaped maze memory evaluation’, which evaluates short-term memory, the concentration-dependent increase in memory, which had decreased after 8 weeks of administration of Kyungokgo, showed a tendency to increase.
Professor Ryu Jong-hoon said, “Gyeongokgo is a drug that has already been clinically proven to be safe,” he said. “The possibility of using Gyeongokgo as a treatment for menopausal syndrome is expected.”
This experiment was conducted using Kwangdong Pharmaceutical’s Gwangdong Gyeongokgo for 7 months from May 2018. The research results were published in Natural Product Sciences of the Korean Society of Pharmacopoeia.
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