Costel Atanasiu, a Romanian virologist with studies in Great Britain, USA and Romania, employee of the Wistar Biomedical Research Institute in the United States, where cancer and infectious diseases are mainly researched, explains on his personal Facebook account how vaccines used to prevent infection work with SARS-CoV-2.
Atanasiu is trying to show the difference between the vaccines currently authorized in Romania and the one produced by AstraZeneca, which is being authorized.
“It’s time to talk about the Astra-Zeneca-Oxford vaccine, the so-called classic vaccine. It’s not really a classic one! The classic one would be made with SARS-CoV-2 viral particles grown on human cells and then incited with Then, those dead viruses would be introduced into the body through the vaccine, but the AZ vaccine uses a different method, using a chimpanzee adenovirus as a transport vector, in which only the spike protein gene is cloned. “It’s very instructive. We are now injecting the adenovirus + spike gene into the body. What’s going on?”, says the Romanian virologist at the beginning of the post.
Atanasiu later explains that he addresses the current opinion according to which the next vaccine that will arrive on the market, the one from AstraZeneca, is recommended because it would be the classic vaccine: “If you are a conspirator, you should be afraid of AZ. “.
“Adenovirus enters the human cell and then attaches to the nuclear membrane and pours its contents into the nucleus. Remember, adenovirus and spike protein are in DNA format and are located in the same compartment as human DNA. Theoretically, in this case it is possible that Adenovirus DNA + spike DNA to integrate into the human genome No reverse transcription from mRNA to DNA is needed, no translocation (migration) of this DNA to the nucleus is needed as fabled by those whose “It’s a fear of the Pfizer vaccine. Everything is ready for possible integration. In theory, this is not the case. The AZ vaccine is also safe.”
Wait and see what happens to this viral DNA. How do you think the spike protein will be synthesized? (Now I’m really laughing out loud). You guessed it, a copy of … messenger RNA will first be synthesized from the viral DNA (vector plus spike). This messenger RNA will be transported to the cytoplasm where it will meet the ribosomes that will produce the spike protein.
So in the end you still can’t get rid of the infamous messenger RNA! You can’t help it! Ribosomes can only read RNA.
So the vaccine from Pfizer and Moderna eliminates a step, that of transcription, of copying information from DNA to mRNA. In addition, the Pfizer vaccine reaches the cytoplasm directly and NEVER enters the nucleus, “says Costel Atanasiu at the end of the post.
On the same topic:
Comparison of AstraZeneca and Pfizer-BioNTech vaccines: efficacy, price and storage
Testing of the combination of COVID Sputnik V-AstraZeneca vaccines will begin in February
The European Medicines Agency has received an application for authorization of the AstraZeneca-Oxford vaccine
Source: Breaking News – Cele mai importante stiri – Ziare.com by ziare.com.
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