How long does coffee affect and refresh?

Caffeine reaches its peak in the blood in about 30 to 60 minutes. 1-2 cups of coffee is enough. The amount of caffeine in the blood is halved in 5 to 8 hours.

However, the half-life is individual. It is affected by the absorption and transport of caffeine into the bloodstream and by enzyme-regulated caffeine metabolism.

The invigorating effect of caffeine is also individual. Someone can drink coffee in the pot without refreshing, another half a cup is effective. About a third of us are sensitive to caffeine and another third are moderately sensitive. After all, caffeine works poorly, if at all.

Content continues after ad

The difference is related to genetic factors, i.e., individually acting cellular adenosine receptors to which both adenosine and caffeine bind. Adenosine is the brain’s sands of sleep. When it accumulates in nerve cells, it begins to get tired. If caffeine blocks the receptors, falling asleep is prevented and only succeeds when caffeine is broken down in the body.

The content continues below the ad

As a defendant
Tarja Stenberg,
Docent of Physiology, University of Helsinki.

Published in Science Journal 8/2021

Source: Tiede by

*The article has been translated based on the content of Tiede by If there is any problem regarding the content, copyright, please leave a report below the article. We will try to process as quickly as possible to protect the rights of the author. Thank you very much!

*We just want readers to access information more quickly and easily with other multilingual content, instead of information only available in a certain language.

*We always respect the copyright of the content of the author and always include the original link of the source article.If the author disagrees, just leave the report below the article, the article will be edited or deleted at the request of the author. Thanks very much! Best regards!