Efluelda: a “beefier” flu vaccine for seniors


People over 65 will be able to get the flu shot starting October 26. This year, they will be able to benefit from a “high dose” vaccine, Efluelda, which prevents 24% more flu.

Each year, the flu kills 10,000 people in France, including 9,000 over the age of 65. Aging and the increased frequency of comorbidities (diabetes, cardiovascular disease, renal failure, etc.) make seniors a particularly sensitive target to influenza viruses. In addition to a risk of mortality, seniors must also face complications: acute respiratory distress syndrome, bacterial superinfection, decompensation of comorbidities, functional dependence … “Between 2012 and 2017, half of the patients hospitalized for influenza were aged 60 years and over “underlines the Sanofi Pasteur laboratory.

Efluelda: a more highly dosed vaccine

In people 65 years of age and over, the influenza vaccines used so far provide a suboptimal immune response compared to that seen in young adults, due in part to the progressive deterioration of the immune system, which lasts. age. To compensate for what is called the “phenomenon of immunosenescence”, a new, more highly dosed vaccine (Efluelda from the Sanofi Pasteur laboratory) has obtained marketing authorization. It contains four strains of influenza virus: two type A (H1N1 and H3N2) and two type B. It is recommended for use by people 65 years of age and over.

Why a “high dose” vaccine for seniors?

The high dose influenza vaccine (HD) is currently authorized and recommended in its trivalent form in several countries (including Australia, Canada, United States and United Kingdom). Its effectiveness was evaluated there in 32,000 people aged 65 and over during two influenza seasons. Compared to the standard dose vaccine, the high dose vaccine prevented 24.2% more cases of influenza.

This HD vaccine is available for the 2021 vaccination campaign which will start on October 26. The vaccine is 100% reimbursable by Health Insurance for all so-called “at-risk” people who have received a care voucher.

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Source: Topsante.com by www.topsante.com.

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