7 chronic diseases at high risk of death


Among the co-morbidities, which are the ones that put the highest risk of dying from Covid-19? To find out, a study carried out among 66 million people by the National Medicines Agency and the Primary Health Insurance Fund on the first wave of the epidemic (from February 15 to June 15, 2020) analyzed the link between 47 chronic diseases and the risk of developing a severe form of Covid-19.

The results confirm that the elderly are by far the most fragile. But other profiles are also very vulnerable. Thus “almost all chronic conditions are associated with increased risks of hospitalization and death for Covid-19”, note the authors.

And among the seven pathologies most at risk, trisomy 21 leads with 7 times the risk of hospitalization and 23 times the risk of death. Reason why those concerned can be vaccinated since January 18.

Then follow:

– mental retardation (4 times more risk of hospitalization and 7 times more risk of death);

– cystic fibrosis (4 times more risk of hospitalization and 6 times more risk of death);

– end-stage chronic renal failure on dialysis (4 times more risk of hospitalization and 5 times more risk of death);

– active lung cancer (3 times more risk of hospitalization and 4 times more risk of death);

– kidney transplantation (5 times more risk of hospitalization and 7 times more risk of death) or lung transplantation (3 times more risk of hospitalization and 6 times more risk of death).

How to explain this extreme fragility in the case of trisomy 21?

“From the age of 40, it is undoubtedly linked to the premature aging of adults with Down’s syndrome”, indicated Renaud Touraine, the head of the clinical chromosomal and molecular genetic service, at the Saint-Étienne University Hospital, to our colleagues from Faire-Face magazine, live better with disability. As a result, pathologies observed in the elderly occur earlier in these people. Not to mention that “their immune system is often dysfunctional,” continues Renaud Touraine.


Source: A la Une – Le Progrès | Le Progrès by www.leprogres.fr.

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